Silazane | Silylating Agent | Pharmaceutical Manufacturing | Silane Blocking Agents
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| SiSiB® PC9210
Hexamethyldisilazane.
Synonym: Bis(trimethylsilyl)amine; HMDS; HMDZ
Countertype of Dynasylan HMDS, DowCorning Z-6079, ShinEtsu HMDS3, Silquest A-166
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SiSiB® silazane is any hydride of silicon and nitrogen having a straight or branched chain of silicon and nitrogen atoms joined by covalent bonds. By extension, the word is also used for any organic derivative of such compounds. They are analogous to siloxanes, with -NH- replacing -O-. Their individual name is dependent on the number of silicon atoms in the chemical structure.
SiSiB® PC9210 (HMDS) is an extremely versatile and strong silylating agent. It is primarily used for the protection of sensitive functional groups during chemical synthesis.
Trimethylsilyl moiety is a versatile blocking agent employed in chemical synthesis. Introduction of silyl protective groups has following advantages:
Masking of reactive functional groups.
Improvement of solubility in polar and or non polar solvent.
Improved product stability.
Easy removal of protective groups .
Additional activation of reactive centres.
Easyelimination of hydrogen bonds.
One of the advantages of SiSiB® PC9210 over chlorosilanes is that no base is needed as a hydrochloric acid acceptor. SiSiB® PC9210 produces ammonia which escapes easily from the reaction mixture during silylation.
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| Typical Physical Properties |
| Chemical Name: |
Hexamethyldisilazane |
| CAS No.: |
999-97-3 |
| EINECS No.: |
213-668-5 |
| Empirical Formula: |
C6H19NSi2 |
| Molecular Weight: |
161.39 |
| Boiling Point: |
126°C [760mmHg] |
| Flash Point: |
15°C |
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| Color and Appearance: |
Clear liquid with ammonia odor |
| Density [25°C]: |
0.774 |
| Refractive Index [25°C]: |
1.4080 |
| Purity: |
99% by GC |
SiSiB® silanes are versatile materials used in a wide range of applications including:
Silane Coupling Agent, Silane Adhesion Promoter, Silane Hydrophobing Agent, Silane Dispersing Agent, Silane Crosslinking Agent, Silane Moisture Scavenger, Polypropylene Catalyst "Donor" Silane, Silicate Stabilizer, Polyurethane Endcapper Silane, Silane Drying Agent, Silane Curing Agent, Silane Reinforcer, Silylating Agent, Silane Reducing Agent, Silyl Building Blocks and Synthons etc.
SiSiB® PC9210 is the most commonly used reagent for silylation of protic organic and inorganic materials.
SiSiB® PC9210 is used as adhesion promoter in the
microelectronic industry.
SiSiB® PC9210 is used as hydrophobing agent for
for fillers.
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Net weight 210L steel drum or 1000L IBC container, for more details, please visit Packing Centre.
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